Article
Gene-environment interaction for childhood asthma and exposure to farming in Central Europe.
The Journal of allergy and clinical immunology - 1 Jan 2011
Ege Markus J, Strachan David P, Cookson William O C M, Moffatt Miriam F, Gut Ivo, Lathrop Mark, Kabesch Michael, Genuneit Jon, Büchele Gisela, Sozanska Barbara, Boznanski Andrzej, Cullinan Paul, Horak Elisabeth, Bieli Christian, Braun-Fahrländer Charlotte, Heederik Dick, von Mutius Erika
Abstract excerpt
BACKGROUND: Asthma is a disease in which both genetic and environmental factors play important roles. The farming environment has consistently been associated with protection from childhood asthma and atopy, and interactions have been reported with polymorphisms in innate immunity genes. OBJECTIVE: To detect gene-environment interactions for asthma and atopy in the farming environment. METHODS: We performed a...
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