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Article

Gene-environment interactions in the development of asthma and atopy.

Expert review of respiratory medicine - 1 Jun 2012

Custovic Adnan, Marinho Susana, Simpson Angela

Abstract excerpt

Asthma is a complex multifactorial disorder involving a variety of different mechanisms. Little has changed in asthma treatment over the past five decades. There is evidence for a strong genetic component of asthma, but genetic studies have produced heterogeneous results with little replication, with most of the heritability remaining unexplained. The rapid increase in asthma prevalence over a short time period...

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PMID: 22788944
DOI: 10.1586/ers.12.24

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