Article
Gene-environmental interaction in asthma.
Current opinion in allergy and clinical immunology - 1 Feb 2007
Yang Ian A, Savarimuthu Santiyagu, Kim Samuel T, Holloway John W, Bell Scott C, Fong Kwun M
Abstract excerpt
PURPOSE OF REVIEW: Asthma is likely to result from the effects of environmental stimuli in genetically susceptible individuals. This review summarizes recent studies of gene-environmental interaction in the pathogenesis of asthma, focusing on study designs. RECENT FINDINGS: Studies using genetic epidemiology, in-vitro and ex-vivo models and in-vivo model organisms demonstrate that gene-environmental interaction...
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