Article
Asthma in farm children is more determined by genetic polymorphisms and in non-farm children by environmental factors.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Feb 2021
Krautenbacher Norbert, Kabesch Michael, Horak Elisabeth, Braun-Fahrländer Charlotte, Genuneit Jon, Boznanski Andrzej, von Mutius Erika, Theis Fabian, Fuchs Christiane, Ege Markus J
Abstract excerpt
BACKGROUND: The asthma syndrome is influenced by hereditary and environmental factors. With the example of farm exposure, we study whether genetic and environmental factors interact for asthma. METHODS: Statistical learning approaches based on penalized regression and decision trees were used to predict asthma in the GABRIELA study with 850 cases (9% farm children) and 857 controls (14% farm children)....
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