Article
Genetic basis of autoantibody positive and negative rheumatoid arthritis risk in a multi-ethnic cohort derived from electronic health records.
American journal of human genetics - 7 Jan 2011
Kurreeman Fina, Liao Katherine, Chibnik Lori, Hickey Brendan, Stahl Eli, Gainer Vivian, Li Gang, Bry Lynn, Mahan Scott, Ardlie Kristin, Thomson Brian, Szolovits Peter, Churchill Susanne, Murphy Shawn N, Cai Tianxi, Raychaudhuri Soumya, Kohane Isaac, Karlson Elizabeth, Plenge Robert M
Abstract excerpt
Discovering and following up on genetic associations with complex phenotypes require large patient cohorts. This is particularly true for patient cohorts of diverse ancestry and clinically relevant subsets of disease. The ability to mine the electronic health records (EHRs) of patients followed as part of routine clinical care provides a potential opportunity to efficiently identify affected cases and unaffected...
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