Article
Proteasomal degradation of Sfp1 contributes to the repression of ribosome biogenesis during starvation and is mediated by the proteasome activator Blm10.
Molecular biology of the cell - 1 Mar 2011
Lopez Antonio Diaz, Tar Krisztina, Krügel Undine, Dange Thomas, Ros Ignacio Guerrero, Schmidt Marion
Abstract excerpt
The regulation of ribosomal protein (RP) gene transcription is tightly linked to the nutrient status of the cell and is under the control of metabolic signaling pathways. In Saccharomyces cerevisiae several transcriptional activators mediate efficient RP gene transcription during logarithmic growth and dissociate from RP gene promoters upon nutrient limitation. Repression of RP gene transcription appears to be...
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