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Article

A Rab escort protein integrates the secretion system with TOR signaling and ribosome biogenesis.

Genes & development - 15 Aug 2009

Singh Jaspal, Tyers Mike

Abstract excerpt

The coupling of environmental conditions to cell growth and division is integral to cell fitness. In Saccharomyces cerevisiae, the transcription factor Sfp1 couples nutrient status to cell growth rate by controlling the expression of ribosome biogenesis (Ribi) and ribosomal protein (RP) genes. Sfp1 is localized to the nucleus in rich nutrients, but upon nutrient limitation or target of rapamycin (TOR) pathway...

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Identifiers

PMID: 19684114
DOI: 10.1101/gad.1804409
PMCID: PMC2725937

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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