Article
Polymorphisms of CD16A and CD32 Fcγ receptors and circulating immune complexes in Ménière's disease: a case-control study.
BMC medical genetics - 5 Jan 2011
Lopez-Escamez José A, Saenz-Lopez Pablo, Gazquez Irene, Moreno Antonia, Gonzalez-Oller Carlos, Soto-Varela Andrés, Santos Sofía, Aran Ismael, Perez-Garrigues Herminio, Ibañez Agueda, Lopez-Nevot Miguel A
Abstract excerpt
BACKGROUND: Autoimmune diseases with elevated circulating autoantibodies drive tissue damage and the onset of disease. The Fcγ receptors bind IgG subtypes modulating the clearance of circulating immune complexes (CIC). The inner ear damage in Ménière's disease (MD) could be mediated by an immune...
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