Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms in CLEC16A and CIITA at 16p13 are associated with primary adrenal insufficiency.

The Journal of clinical endocrinology and metabolism - 1 Sept 2008

Skinningsrud Beate, Husebye Eystein S, Pearce Simon H, McDonald David O, Brandal Kristin, Wolff Anette B, Løvås Kristian, Egeland Thore, Undlien Dag E

Abstract excerpt

CONTEXT/OBJECTIVES: It is known that different autoimmune diseases often share the same susceptibility genes. In this study we aimed to investigate if loci found associated with common autoimmune diseases in recent genome-wide association studies also could be susceptibility loci for autoimmune Addison's disease (primary adrenal insufficiency). DESIGN/PATIENTS: A total of 139 tagging single nucleotide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Addison Disease
Share to Chromosomes, Human, Pair 16

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lectins, C-Type

Share to Linkage Disequilibrium

Share to Monosaccharide Transport Proteins

Share to Norway

Share to Trans-Activators

Share to United Kingdom

Source

Identifiers

PMID: 18593762
DOI: 10.1210/jc.2008-0821

Genes

CIITA
ERBB3
PTPN11
PTPN2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms in CLEC16A and CIITA at 16p13 are associated with primary adrenal insufficiency.PMID 18593762Read ↗

A CLEC16A variant confers risk for juvenile idiopathic arthritis and anti-cyclic citrullinated peptide antibody negative rheumatoid arthritis.Semantic proximity Read ↗

Chromosomal region 16p13: further evidence of increased predisposition to immune diseases.Semantic proximity Read ↗

Genetic variants at the 16p13 locus confer risk for eosinophilic esophagitisSemantic proximity Read ↗

Association of autoimmune Addison's disease with alleles of STAT4 and GATA3 in European cohorts.Semantic proximity Read ↗

Specific association of a CLEC16A/KIAA0350 polymorphism with NOD2/CARD15(-) Crohn's disease patients.Semantic proximity Read ↗

Extended exome sequencing identifies BACH2 as a novel major risk locus for Addison's diseaseSemantic proximity Read ↗

Multiple Sclerosis Risk Allele in CLEC16A Acts as an Expression Quantitative Trait Locus for CLEC16A and SOCS1 in CD4+ T Cells.Semantic proximity Read ↗

Multiple sclerosis-associated single-nucleotide polymorphisms in CLEC16A correlate with reduced SOCS1 and DEXI expression in the thymus.Semantic proximity Read ↗

GWAS for autoimmune Addison’s disease identifies multiple risk loci and highlights AIRE in disease susceptibilitySemantic proximity Read ↗

Long-range DNA looping and gene expression analyses identify DEXI as an autoimmune disease candidate gene.Semantic proximity Read ↗

Variation within the CLEC16A gene shows consistent disease association with both multiple sclerosis and type 1 diabetes in Sardinia.Semantic proximity Read ↗

Exploring the CLEC16A gene reveals a MS-associated variant with correlation to the relative expression of CLEC16A isoforms in thymus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.