Article
The tendency to recreate ancestral CG dinucleotides in the human genome.
BMC evolutionary biology - 5 Jan 2011
Li Mingkun, Chen Su-Shing
Abstract excerpt
BACKGROUND: The CG dinucleotides are known to be deficient in the human genome, due to a high mutation rate from 5-methylated CG to TG and its complementary pair CA. Meanwhile, many cellular functions rely on these CG dinucleotides, such as gene expression controlled by cytosine methylation statu...
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