Article
Combined genome-wide scan for prostate cancer susceptibility genes.
Journal of the National Cancer Institute - 18 Aug 2004
Gillanders Elizabeth M, Xu Jianfeng, Chang Bao-li, Lange Ethan M, Wiklund Fredrik, Bailey-Wilson Joan E, Baffoe-Bonnie Agnes, Jones MaryPat, Gildea Derek, Riedesel Erica, Albertus Julie, Isaacs Sarah D, Wiley Kathleen E, Mohai Caroline E, Matikainen Mika P, Tammela Teuvo L J, Zheng S Lilly, Brown W Mark, Rökman Annika, Carpten John D, Meyers Deborah A, Walsh Patrick C, Schleutker Johanna, Gronberg Henrik, Cooney Kathleen A, Isaacs William B, Trent Jeffrey M
Abstract excerpt
BACKGROUND: Prostate cancer represents a substantial public health burden worldwide. It is the second leading cause of cancer death among men in the United States. A family history of the disease is among the most well-established risk factors for prostate cancer. Efforts to localize prostate cancer susceptibility alleles by using genetic linkage analysis methods have been hindered by genetic heterogeneity,...
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