Article
Genome-wide linkage scan for prostate cancer susceptibility from the University of Michigan Prostate Cancer Genetics Project: suggestive evidence for linkage at 16q23.
The Prostate - 1 Mar 2009
Lange Ethan M, Beebe-Dimmer Jennifer L, Ray Anna M, Zuhlke Kimberly A, Ellis Jaclyn, Wang Yunfei, Walters Sarah, Cooney Kathleen A
Abstract excerpt
BACKGROUND: Prostate cancer linkage studies have been used to localize rare and presumably highly penetrant cancer susceptibility genes. Underlying genetic heterogeneity, as well as the high sporadic background of the disease, has resulted in many signals that are often not reproducible between research studies. METHODS: We conducted a SNP-based genome wide linkage scan on 131 Caucasian prostate cancer families...
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