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Article

Fine-mapping the putative chromosome 17q21-22 prostate cancer susceptibility gene to a 10 cM region based on linkage analysis.

Human genetics - 1 Mar 2007

Lange Ethan M, Robbins Christiane M, Gillanders Elizabeth M, Zheng Siqun Lilly, Xu Jianfeng, Wang Yunfei, White Kirsten A, Chang Bao-Li, Ho Lindsey A, Trent Jeffrey M, Carpten John D, Isaacs William B, Cooney Kathleen A

Abstract excerpt

Prostate cancer linkage studies have suggested the existence of a prostate cancer susceptibility gene on chromosome 17q21-22. We now report the results of an extended linkage analysis including 95 new multiplex prostate cancer families and 9 additional microsatellite markers resulting in a maximum LOD score of 2.99 at approximately 81-82 cM for all 453 pedigrees. Results from these 95 new pedigrees provide...

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PMID: 17120048
DOI: 10.1007/s00439-006-0274-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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