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Article

Effects of non-iron metalloporphyrins on growth and gene expression of Porphyromonas gingivalis.

Microbiology and immunology - 1 Mar 2011

Yukitake Hideharu, Naito Mariko, Sato Keiko, Shoji Mikio, Ohara Naoya, Yoshimura Mamiko, Sakai Eiko, Nakayama Koji

Abstract excerpt

The oral anaerobic bacterium Porphyromonas gingivalis, which is implicated as an important pathogen for chronic periodontitis, requires heme for its growth. Non-iron metalloporphyrins, In-PPIX and Ga-PPIX, were examined for antibacterial effects on P. gingivalis. Both In-PPIX and Ga-PPIX caused retardation of P. gingivalis growth in a dose-dependent fashion. Microarray and qPCR analyses revealed that In-PPIX...

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Identifiers

PMID: 21204951
DOI: 10.1111/j.1348-0421.2010.00299.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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