Article
Accessory fimbrial subunits and PPAD are necessary for TLR2 activation by Porphyromonas gingivalis
22 Jun 2023
Abstract excerpt
Porphyromonas gingivalis is an oral pathogen that promotes dysbiosis by quenching the bactericidal activity of the host immune system while maintaining chronic inflammation, leading to periodontitis. This involves the secretion of virulence factors such as P. gingivalis peptidyl arginine deiminase (PPAD), which converts the C-terminal Arg residues of bacterial and host-derived proteins and peptides into...
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