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Article

Hemin availability induces coordinated DNA methylation and gene expression changes in <i>Porphyromonas gingivalis</i>

2022-03-14

Abstract excerpt

Periodontal disease is a common chronic inflammatory disease. Porphyromonas gingivalis is an important bacterium in the development of the disease and expresses a variety of virulence determinants. Hemin (iron [III] protopotphyrin IX), an essential nutrient of this organism, whose concentration increases with increasing inflammation, is a global regulator of virulence in P. gingivalis : high hemin levels increas...

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Literature Corpus work
fb1f545e-ccba-5022-ba7c-855ade5e1403
DOI
10.1101/2022.03.14.484211
Open publication

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