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Article

OxyR activation in Porphyromonas gingivalis in response to a hemin-limited environment.

Infection and immunity - 1 Oct 2012

Xie Hua, Zheng Cunge

Abstract excerpt

Porphyromonas gingivalis is a Gram-negative obligately anaerobic bacterium associated with several forms of periodontal disease, most closely with chronic periodontitis. Previous studies demonstrated that OxyR plays an important role in the aerotolerance of P. gingivalis by upregulating the expression of oxidative-stress genes. Increases in oxygen tension and in H(2)O(2) both induce activation of OxyR. It is also...

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Identifiers

PMID: 22825453
DOI: 10.1128/IAI.00680-12
PMCID: PMC3457554

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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