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Article

The PorX/PorY system is a virulence factor of Porphyromonas gingivalis and mediates the activation of the type IX secretion system.

The Journal of biological chemistry - 1 Jan 2000

Yang Dezhi, Jiang Chizhou, Ning Bo, Kong Wei, Shi Yixin

Abstract excerpt

PorX/PorY is a two-component system (TCS) of Porphyromonas gingivalis that governs transcription of numerous genes including those encoding a type IX secretion system (T9SS) for gingipain secretion and heme accumulation. Here, an in vitro analysis showed that the response regulator PorX specifically bound to two regions in the promoter of porT, a known PorX-regulated T9SS gene, thus demonstrating that PorX/PorY...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33757767
DOI: 10.1016/j.jbc.2021.100574
PMCID: PMC8050853

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