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Article

Association between maternal single nucleotide polymorphisms in genes regulating glucose metabolism and risk for neural tube defects in offspring.

Birth defects research. Part A, Clinical and molecular teratology - 1 Jun 2015

Fu Yunting, Wang Lin-lin, Yi Deqing, Jin Lei, Liu Jufen, Zhang Yali, Ren Aiguo

Abstract excerpt

BACKGROUND: Maternal pregestational hyperglycemia, diabetes, and obesity are well-established risk factors for neural tube defects (NTDs). As a common underlying mechanism, the imbalance of glucose homeostasis is directly related to the development of NTDs. Polymorphisms in genes regulating gluco...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25369983
DOI: 10.1002/bdra.23332

Genes

GCKR
HHEX
KCNQ1
LEPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25369983-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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