Article
Copy number variations of chromosome 17p13.1 might be linked to high risk of lung cancer in heavy smokers.
Molecular biology reports - 1 Nov 2011
Lee Minhyeok, Lee Yeiwon, Cho Hyun-Jung, Hong Jeeyoung, Kwon Sun-Jung, Park Chang-Gyo, Lee Hoi-Young, Son Ji-Woong, Kang Jaeku
Abstract excerpt
Lung cancer is the most common cause of cancer death worldwide. Smoking is known as the strongest single factor in the development of lung cancer. However, there are inherited genetic factors that cause different responses to cigarette smoking exposure among individuals. We tried to identify these differences in heavy smokers by examining copy number variations (CNVs) between lung cancer patients and healthy...
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