Article
Alteration in the phenotype of macrophages in the repair of renal interstitial fibrosis in mice.
Nephrology (Carlton, Vic.) - 1 Jul 2011
Kushiyama Taketoshi, Oda Takashi, Yamada Muneharu, Higashi Keishi, Yamamoto Kojiro, Sakurai Yutaka, Miura Soichiro, Kumagai Hiroo
Abstract excerpt
AIM: Renal interstitial fibrosis is the final common pathway determining long-term prognosis of chronic kidney diseases, but its repair process is scarcely understood. Because recent reports indicate that M2 macrophages play important roles in the repair of various tissues, special attention was paid to the phenotypes of infiltrating macrophages in the present study when the histological changes occurring in...
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