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Article

Comparative analysis of pyrosequencing and QMC-PCR in conjunction with high resolution melting for KRAS/BRAF mutation detection.

International journal of experimental pathology - 1 Dec 2010

Ibrahem Salih, Seth Rashmi, O'Sullivan Brendan, Fadhil Wakkas, Taniere Philippe, Ilyas Mohammad

Abstract excerpt

Mutation detection is important in cancer management. Several methods are available of which high resolution melting (HRM) analysis and pyrosequencing are the most versatile. We undertook a comparative analysis of these techniques. The methods are: To compare the limit of detection (LOD), mutatio...

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Source

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Identifiers

PMID: 21199003
DOI: 10.1111/j.1365-2613.2010.00733.x
PMCID: PMC3010548

Genes

KRAS
BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21199003-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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