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Article

A fast, sensitive and accurate high resolution melting (HRM) technology-based assay to screen for common K-ras mutations.

Cellular oncology : the official journal of the International Society for Cellular Oncology - 1 Jan 2009

Kramer D, Thunnissen F B, Gallegos-Ruiz M I, Smit E F, Postmus P E, Meijer C J L M, Snijders P J F, Heideman D A M

Abstract excerpt

BACKGROUND: Increasing evidence points to a negative correlation between K-ras mutations and patient's response to, or survival benefit after, treatment with EGFR-inhibitors. Therefore, rapid and reliable assays for mutational analysis of the K-ras gene are strongly needed. METHODS: We designed a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19478384
DOI: 10.3233/CLO-2009-0466
PMCID: PMC4618824

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19478384-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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