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Article

Incidence and prognostic importance of molecular genetic defects in children with acute myeloblastic leukemia.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2010

Kömür Mustafa, Erbey Fatih, Bayram Ibrahim, Tanyeli Atila

Abstract excerpt

INTRODUCTION: Acute myeloblastic leukemia (AML) accounts for 15 to 25 percent of childhood acute leukemias. The most common genetic abnormalities seen in pediatric AML patients are AML1-ETO, PML-RARα and CBFB-MYH11 genes resulting in t(8;21), t(15;17) and inv(16). These genetic defects are seen in approximately 20-25% of AML patients. OBJECTIVE: We investigated in this study, incidence and prognostic significance...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21198299

Genes

CBFB
MYH11
PML

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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