Article
Different effects of redundant feedback loops on a bistable switch.
Chaos (Woodbury, N.Y.) - 1 Dec 2010
Domingo-Sananes Maria Rosa, Novak Bela
Abstract excerpt
Bistable switches have important roles in cellular decision-making processes. Bistability can be the consequence of positive or double-negative feedback loops. Although necessary, such feedback is not sufficient for bistability, which also requires nonlinearity. Nonlinearity can be provided by synergy of multiple feedback loops or by an ultrasensitive response within a single feedback loop. However, these two...
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