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Article

Passage of low-pathogenic avian influenza (LPAI) viruses mediates rapid genetic adaptation of a wild-bird isolate in poultry.

Archives of virology - 1 Apr 2011

Dlugolenski Daniel, Jones Les, Saavedra Geraldine, Tompkins S Mark, Tripp Ralph A, Mundt Egbert

Abstract excerpt

For a better understanding of evolution of influenza viruses, a chicken-origin and wild-bird-origin low-pathogenic avian influenza virus (LPAI) was serially passaged in chickens. Sequences of the hemagglutinin (HA) and neuraminidase (NA) genes at each passage level were compared to those of the parental virus. Multiple mutations occurring early during passage were detected, but these were maintained during...

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Identifiers

PMID: 21197555
DOI: 10.1007/s00705-010-0891-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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