Article
H9N2 avian influenza virus retained low pathogenicity after serial passage in chickens.
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire - 1 Apr 2018
Jegede Akinlolu, Fu Qigao, Berhane Yohannes, Lin Min, Kumar Ashok, Guan Jiewen
Abstract excerpt
The H9N2 strains of avian influenza viruses (AIVs) circulate worldwide in poultry and cause sporadic infection in humans. To better understand the evolution of these viruses while circulating in poultry, an H9N2 chicken isolate was passaged 19 times in chickens via aerosol inoculation. Whole-genome sequencing showed that the viruses from the initial stock and those after the 8th and 19th passages (P0, P8, and...
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