Article
Selection of antigenic variants of an H5N1 highly pathogenic avian influenza virus in vaccinated chickens.
Virology - 1 Oct 2017
Nguyen Lam Thanh, Nishi Tatsuya, Shichinohe Shintaro, Chu Duc-Huy, Hiono Takahiro, Matsuno Keita, Okamatsu Masatoshi, Kida Hiroshi, Sakoda Yoshihiro
Abstract excerpt
Vaccination-primed immunity in poultry has been suggested for selection of antigenically drifted highly pathogenic avian influenza viruses (HPAIVs). In this study, we performed two consecutive passage studies of an H5N1 HPAIV in vaccinated chickens, namely, study-I and study-II, to select antigenic variants under immune pressure from the vaccination. In study-I, nine consecutive passages of a wild-type H5N1 HPAIV...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
