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Article

Replication and adaptive mutations of low pathogenic avian influenza viruses in tracheal organ cultures of different avian species.

PloS one - 1 Jan 2012

Petersen Henning, Matrosovich Mikhail, Pleschka Stephan, Rautenschlein Silke

Abstract excerpt

Transmission of avian influenza viruses (AIV) between different avian species may require genome mutations that allow efficient virus replication in a new species and could increase virulence. To study the role of domestic poultry in the evolution of AIV we compared replication of low pathogenic (LP) AIV of subtypes H9N2, H7N7 and H6N8 in tracheal organ cultures (TOC) and primary embryo fibroblast cultures of...

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Identifiers

PMID: 22912693
DOI: 10.1371/journal.pone.0042260
PMCID: PMC3418272

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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