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Article

p53 functional activation is independent of its genotype in five esophageal squamous cell carcinoma cell lines.

Frontiers of medicine in China - 1 Dec 2010

Ji Junfang, Wu Kun, Wu Min, Zhan Qimin

Abstract excerpt

p53 mutations have been found in many esophageal squamous cell carcinoma (ESCC) clinical specimens and cell lines. We reasoned that functional inactivation of wild-type p53 or the functional activation of mutant-type p53 might exist in these specimens and cell lines. In this study, we identified the correlation between p53 functional activation and its genotype in five different ESCC cell lines. To examine the...

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Source

Identifiers

PMID: 21191746
DOI: 10.1007/s11684-010-0260-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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