Article
Variation in SNPs of the IL7Ra gene is associated with multiple sclerosis in the Iranian population.
Immunological investigations - 1 Jan 2011
Heidari Moones, Behmanesh Mehrdad, Sahraian Mohammad-Ali
Abstract excerpt
Interleukin-7 receptor-alpha gene (IL7Ra) is a member of the type I cytokine receptor family located on 5p13 human chromosome. Some evidence associates multiple sclerosis and single nucleotide polymorphisms in the promoter and exonic region of IL7Ra gene. In an attempt to clarify this association, the frequency of 3 SNPs located in the promoter and 1 SNP located in the 6th exon of IL7Ra gene were analyzed in a...
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