Article
Interleukin 7 Receptor Alpha Gene Variants Are Correlated with Gene Expression in Patients with Relapsing-remitting Multiple Sclerosis.
Iranian journal of allergy, asthma, and immunology - 1 Aug 2017
Sayad Arezou, Omrani Mir Davood, Solgi Ghasem, Noroozi Rezvan, Arsang-Jang Shahram, Inoko Hidetoshi, Taheri Mohammad
Abstract excerpt
The association of single nucleotide polymorphisms (SNPs) of the IL-7Rα gene with multiple sclerosis (MS) have been documented in various populations. This study aimed to evaluate the genotype distributions of two SNPs, rs6897932 and rs201084372, and the functional association of rs6897932 in relation to IL-7Rα gene expression in a group of Iranian relapsing-remitting MS (RRMS) patients. Genotyping for both SNPs...
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