Article
Genetic variants in interleukin 7 receptor α chain (IL-7Ra) are associated with multiple sclerosis risk and disability progression in Central European Slovak population.
Journal of neuroimmunology - 15 May 2015
Čierny Daniel, Hányšová Sandra, Michalik Jozef, Kantorová Ema, Kurča Egon, Škereňová Mária, Lehotský Ján
Abstract excerpt
In this study, we determined the association between rs6897932 in interleukin 7 receptor α (IL7Ra) gene and the risk and disability progression of multiple sclerosis (MS) in 270 MS patients and 303 controls. We found allele C to be associated with the risk of MS and minor allele T to be protective against MS development. Moreover, we revealed for the first time that rs6897932 in IL7Ra gene is associated with the...
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