The promoter SNP, but not the alternative splicing SNP, is linked to multiple sclerosis among Jordanian patients.

doi:10.1007/s12031-013-0151-0

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Article

The promoter SNP, but not the alternative splicing SNP, is linked to multiple sclerosis among Jordanian patients.

Journal of molecular neuroscience : MN - 1 Apr 2014

Ibayyan Leena, Zaza Rand, Dahbour Said, El-Omar Ammar, Samhouri Bilal, El-Khateeb Mohammad, Ahram Mamoun

Abstract excerpt

Multiple sclerosis is a chronic inflammatory autoimmune disease of the human central nervous system. A number of studies with compelling evidence have provided correlation between single nucleotide polymorphisms in interleukin-7 receptor alpha and multiple sclerosis (MS) in several populations. One such variation, rs6897932, is located within the coding region and results in the generation of a soluble receptor,...

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PMID: 24166352
DOI: 10.1007/s12031-013-0151-0

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