Article
CD133+ niches and single cells in glioblastoma have different phenotypes.
Journal of neuro-oncology - 1 Aug 2011
Christensen Karina, Schrøder Henrik Daa, Kristensen Bjarne Winther
Abstract excerpt
Putative CD133(+) brain tumor stem cells have been shown to be located in niches and as single cells. This is the first study providing insight into the different phenotypes of CD133(+) cells in glioblastoma according to localization. Paraffin sections were stained by double immunofluorescence with CD133 and the candidate stem cell markers Sox2, Bmi-1, EGFR, podoplanin and nestin, the proliferation marker Ki67...
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