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The role of cancer stem cells in glioblastoma

1 Dec 2014

Abstract excerpt

Recurrence in glioblastoma is nearly universal, and its prognosis remains dismal despite significant advances in treatment over the past decade. Glioblastoma demonstrates considerable intratumoral phenotypic and molecular heterogeneity and contains a population of cancer stem cells that contributes to tumor propagation, maintenance, and treatment resistance. Cancer stem cells are functionally defined by their...

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Identifiers

PMID: 25434391
DOI: 10.3171/2014.9.focus14494

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