Article
A distinct subpopulation within CD133 positive brain tumor cells shares characteristics with endothelial progenitor cells.
Cancer letters - 28 Nov 2012
Choi Seung Ah, Wang Kyu-Chang, Phi Ji Hoon, Lee Ji Yeoun, Park Chul-Kee, Park Sung-Hye, Kim Seung-Ki
Abstract excerpt
The cell surface marker CD133 has been proposed as a brain tumor stem cell marker. However, there have been substantial controversies regarding the necessity and role of CD133 in tumorigenesis. This study aimed to characterize CD133(+) cells in brain tumors. Human brain tumor specimens and whole blood were collected from the same patients (N=12). We carried out dual FACS staining for CD133/CD34 and functional...
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