Clonal variation of adenylyl cyclase activity in a rat tumor cell line caused by change in G protein-catalytic unit interaction.

doi:10.1002/jcp.1041440312

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Article

Clonal variation of adenylyl cyclase activity in a rat tumor cell line caused by change in G protein-catalytic unit interaction.

Journal of cellular physiology - 1 Sept 1990

Kawabata M, Yoshikura H, Horio K, Fujiwara K, Iwamoto A

Abstract excerpt

Two subclones of the rat XC cell line characterized by different morphology exhibited quite different adenylyl cyclase responses upon various stimulations. Upon treatment with cholera toxin, clone RK1 accumulated a high level of intracellular cAMP thereby changing its polygonal morphology to an e...

Topics

Adenosine Diphosphate Ribose
Adenylyl Cyclases
Animals
Catalysis
Cell Membrane
Cholera Toxin
Clone Cells
Colforsin
GTP-Binding Proteins
Gene Expression
Genetic Variation
Rats
Rats, Inbred Strains
Sarcoma, Experimental
Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 2118146
DOI: 10.1002/jcp.1041440312

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2118146-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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