Article
The genetic variant on chromosome 10p14 is associated with risk of colorectal cancer: results from a case-control study and a meta-analysis.
PloS one - 1 Jan 2013
Qin Qin, Liu Li, Zhong Rong, Zou Li, Yin Jieyun, Zhu Beibei, Cao Beibei, Chen Wei, Chen Jigui, Li Xiaorong, Li Tingting, Lu Xuzai, Lou Jiao, Ke Juntao, Wei Sheng, Miao Xiaoping, Nie Shaofa
Abstract excerpt
BACKGROUND: A common single nucleotide polymorphism (SNP), rs10795668, located at 10p14, was first identified to be significantly associated with risk of colorectal cancer (CRC) by a genome-wide association study (GWAS) in 2008; however, another GWAS and following replication studies yielded conflicting results. METHODS: We conducted a case-control study of 470 cases and 475 controls in a Chinese population and...
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