Article
Replication study in Chinese population and meta-analysis supports association of the 11q23 locus with colorectal cancer.
PloS one - 1 Jan 2012
Zou Li, Zhong Rong, Lou Jiao, Lu Xuzai, Wang Qi, Yang Yang, Xia Jiahong, Ke Juntao, Zhang Ti, Sun Yu, Liu Li, Cui Yongping, Xiao Haibing, Chang Lei, Xia Ding, Xu Hua
Abstract excerpt
BACKGROUND: A common single nucleotide polymorphism (SNP), rs3802842, located at 11q23, was identified by genome-wide association studies (GWAS) to be significantly associated with the risk of colorectal cancer (CRC); however, the results of following replication studies were not always concordant. Thus, a case-control study and a meta-analysis were performed to clearly discern the effect of this variant in CRC....
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