Article
CDKN1B V109G polymorphism a new prognostic factor in sporadic medullary thyroid carcinoma.
European journal of endocrinology - 1 Mar 2011
Pasquali Daniela, Circelli Luisa, Faggiano Antongiulio, Pancione Massimo, Renzullo Andrea, Elisei Rossella, Romei Cristina, Accardo Giacomo, Coppola Viviana Raffaella, De Palma Maurizio, Ferolla Piero, Grimaldi Franco, Colao Annamaria, Colantuoni Vittorio
Abstract excerpt
CONTEXT: CDKN1B encodes the cyclin-dependent kinase inhibitor p27Kip1 and is mutated in multiple endocrine neoplasia-like syndromes. CDKN1B also harbors single nucleotide polymorphisms; the T/G transversion at nucleotide 326 (the V109G variant) has been reported to be protective in breast, heredi...
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