Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphisms of cell cycle control genes influence the development of sporadic medullary thyroid carcinoma.

European journal of endocrinology - 1 Dec 2014

Barbieri R B, Bufalo N E, Secolin R, Assumpção L V M, Maciel R M B, Cerutti J M, Ward L S

Abstract excerpt

BACKGROUND: The role of key cell cycle regulation genes such as, CDKN1B, CDKN2A, CDKN2B, and CDKN2C in sporadic medullary thyroid carcinoma (s-MTC) is still largely unknown. METHODS: In order to evaluate the influence of inherited polymorphisms of these genes on the pathogenesis of s-MTC, we used TaqMan SNP genotyping to examine 45 s-MTC patients carefully matched with 98 controls. RESULTS: A multivariate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Neuroendocrine
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Cycle Checkpoints

Share to Cell Cycle Proteins

Share to Neoplasm Invasiveness

Share to Neoplasm Metastasis

Share to Polymorphism, Single Nucleotide

Share to Thyroid Neoplasms

Source

Identifiers

PMID: 25565272
DOI: 10.1530/EJE-14-0461

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphisms of cell cycle control genes influence the development of sporadic medullary thyroid carcinoma.PMID 25565272Read ↗

Genetics of Familial Non-Medullary Thyroid Carcinoma (FNMTC)Semantic proximity Read ↗

Modulatory Role of Single Nucleotide Polymorphisms of Distinct Genetic Pathways on Clinical Behavior of Medullary Thyroid Carcinoma.Semantic proximity Read ↗

Genetics of medullary thyroid cancer: An overview.Semantic proximity Read ↗

Role of CDKN2C Copy Number in Sporadic Medullary Thyroid Carcinoma.Semantic proximity Read ↗

Additive effect of RET polymorphisms on sporadic medullary thyroid carcinoma susceptibility and tumor aggressiveness.Semantic proximity Read ↗

Allelic variant at -79 (C>T) in CDKN1B (p27Kip1) confers an increased risk of thyroid cancer and alters mRNA levels.Semantic proximity Read ↗

Molecular genetics of thyroid cancer.Semantic proximity Read ↗

Genetic Mutations and Variants in the Susceptibility of Familial Non-Medullary Thyroid Cancer.Semantic proximity Read ↗

Genetic susceptibility to hereditary non-medullary thyroid cancerSemantic proximity Read ↗

Association study of 69 genes in the ret pathway identifies low-penetrance loci in sporadic medullary thyroid carcinoma.Semantic proximity Read ↗

Evidence that polymorphisms in detoxification genes modulate the susceptibility for sporadic medullary thyroid carcinoma.Semantic proximity Read ↗

Association studies in thyroid cancer susceptibility: are we on the right track?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.