Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Long-term outcome of "prophylactic therapy" for familial medullary thyroid cancer.

Surgery - 1 Nov 2009

Schellhaas Elisabeth, König Charlotte, Frank-Raue Karin, Buhr Heinz-J, Hotz Hubert G

Abstract excerpt

BACKGROUND: About one quarter of all medullary thyroid cancers (MTC) are determined genetically due to a mutation in the RET proto-oncogene. The most common site of mutation is in codon 634. Therapeutic approaches toward patients at risk for the development of MTC identified by family screening programs range from total thyroidectomy to total thyroidectomy with lymphadenectomy of all 4 compartments. METHODS: We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Neck
Share to Calcitonin
Share to Carcinoma, Medullary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymph Node Excision

Share to Proto-Oncogene Mas

Share to Proto-Oncogene Proteins c-ret

Share to Thyroid Gland

Share to Thyroidectomy

Source

Identifiers

PMID: 19744457
DOI: 10.1016/j.surg.2009.06.007

Genes

RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Long-term outcome of "prophylactic therapy" for familial medullary thyroid cancer.PMID 19744457Read ↗

[Prophylactic thyroidectomy in children and young people with hereditary medullary thyroid carcinoma: a Chilean experience].Semantic proximity Read ↗

Prophylactic thyroidectomy in MEN 2A syndrome: experience in a single center.Semantic proximity Read ↗

Role of prophylactic thyroidectomy in RET 790 familial medullary thyroid carcinoma.Semantic proximity Read ↗

Normal thyroid pathology in patients undergoing thyroidectomy for finding a RETgene germline mutation: a report of three cases and review of the literature.Semantic proximity Read ↗

Utility of serum thyroglobulin measurements after prophylactic thyroidectomy in patients with hereditary medullary thyroid cancer.Semantic proximity Read ↗

[Prophylactic thyroidectomy in medullary thyroid cancer].Semantic proximity Read ↗

Long-term outcome in 46 gene carriers of hereditary medullary thyroid carcinoma after prophylactic thyroidectomy: impact of individual RET genotype.Semantic proximity Read ↗

Early, Prophylactic Thyroidectomy in Hereditary Medullary Thyroid Carcinoma: A 26-year Monoinstitutional Experience.Semantic proximity Read ↗

Prophylactic thyroidectomy in ethnic Chinese patients with multiple endocrine neoplasia type 2A syndrome after the introduction of genetic testing.Semantic proximity Read ↗

Early Malignant Progression of Hereditary Medullary Thyroid CancerSemantic proximity Read ↗

Prophylactic thyroidectomy for asymptomatic 3-year-old boy with positive multiple endocrine neoplasia type 2A mutation (codon 634).Semantic proximity Read ↗

Do Prognostic Differences Exist Among High-Risk RET Mutations? A Comparison of Outcomes Between the RET C634R and Other C634 Mutations in Hereditary Medullary Thyroid Carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.