Article
Phosphoinositides direct equine infectious anemia virus gag trafficking and release.
Traffic (Copenhagen, Denmark) - 1 Apr 2011
Fernandes Fiona, Chen Kang, Ehrlich Lorna S, Jin Jing, Chen Min H, Medina Gisselle N, Symons Marc, Montelaro Ronald, Donaldson Julie, Tjandra Nico, Carter Carol A
Abstract excerpt
Phosphatidylinositol 4,5-biphosphate [PI(4,5)P(2) ], the predominant phosphoinositide (PI) on the plasma membrane, binds the matrix (MA) protein of human immunodeficiency virus type 1 (HIV-1) and equine infectious anemia virus (EIAV) with similar affinities in vitro. Interaction with PI(4,5)P(2)...
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