Article
Analysis of low-frequency mutations associated with drug resistance to raltegravir before antiretroviral treatment.
Antimicrobial agents and chemotherapy - 1 Mar 2011
Liu Jia, Miller Michael D, Danovich Robert M, Vandergrift Nathan, Cai Fangping, Hicks Charles B, Hazuda Daria J, Gao Feng
Abstract excerpt
Raltegravir is highly efficacious in the treatment of HIV-1 infection. The prevalence and impact on virologic outcome of low-frequency resistant mutations among HIV-1-infected patients not previously treated with raltegravir have not been fully established. Samples from HIV treatment-experienced...
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