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Article

TDP-43 is directed to stress granules by sorbitol, a novel physiological osmotic and oxidative stressor.

Molecular and cellular biology - 1 Mar 2011

Dewey Colleen M, Cenik Basar, Sephton Chantelle F, Dries Daniel R, Mayer Paul, Good Shannon K, Johnson Brett A, Herz Joachim, Yu Gang

Abstract excerpt

TDP-43, or TAR DNA-binding protein 43, is a pathological marker of a spectrum of neurodegenerative disorders, including amyotrophic lateral sclerosis and frontotemporal lobar degeneration with ubiquitin-positive inclusions. TDP-43 is an RNA/DNA-binding protein implicated in transcriptional and posttranscriptional regulation. Recent work also suggests that TDP-43 associates with cytoplasmic stress granules, which...

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Identifiers

PMID: 21173160
DOI: 10.1128/MCB.01279-10
PMCID: PMC3067820

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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