Article
Serotonin 5-HT1B receptor gene and attention deficit hyperactivity disorder in Chinese Han subjects.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jan 2005
Li Jun, Wang Yufeng, Zhou Rulun, Zhang Haobo, Yang Li, Wang Bing, Khan Sajjad, Faraone Stephen V
Abstract excerpt
Serotonin is an endogenous neurotransmitter that regulates aggressive and impulsive behavior and may be involved in the development of attention deficit hyperactivity disorder (ADHD). 5-HT1B knockout mice display hyperactivity, increased exploratory activity and aggression, reduced anxiety, increased vulnerability to cocaine self-administration, and elevated alcohol consumption. Many of these same behaviors are...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.