Article
The relationship between serotonin receptor 1B polymorphisms A-161T and alcohol dependence.
Alcoholism, clinical and experimental research - 1 Sept 2009
Lee Sheng-Yu, Lin Wei-Wen, Huang San-Yuan, Kuo Po-Hsiu, Wang Chen-Lin, Wu Pei-Lin, Chen Shiou-Lan, Wu Jo Yung-Wei, Ko Huei-Chen, Lu Ru-Band
Abstract excerpt
BACKGROUND: Several studies have suggested that the serotonin receptor 1B gene (5HT1B) may be important in the pathogenesis of alcohol dependence (alcoholism; ALC; AD). We examined whether 5HT1B gene A-161T polymorphisms (rs130058) are a susceptibility factor for total AD and subgroups of AD. We further explored correlation of this 5HT1B gene variant between anxiety-depression alcoholism (ANX/DEP ALC) and...
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