Article
Genetic variation in angiotensin-converting enzyme-related pathways associated with sudden cardiac arrest risk.
Heart rhythm - 1 Sept 2009
Sotoodehnia Nona, Li Guo, Johnson Catherine O, Lemaitre Rozenn N, Rice Kenneth M, Rea Thomas D, Siscovick David S
Abstract excerpt
BACKGROUND: Angiotensin-converting enzyme (ACE)-related pathways influence arrhythmias and sudden cardiac arrest (SCA) risk. OBJECTIVE: The purpose of this study was to investigate whether genetic variations in ACE-related pathways are associated with SCA risk. Because these pathways are sex dependent and are influenced by estrogen, we examined these genotype-SCA associations in the full study population and...
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