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Article

Pyrosequencing allows the detection of emergent ganciclovir resistance mutations after HCMV infection.

Medical microbiology and immunology - 1 May 2011

Kampmann Susanne E, Schindele Birgit, Apelt Luise, Bührer Christoph, Garten Lars, Weizsaecker Katharina, Krüger Detlev H, Ehlers Bernhard, Hofmann Jörg

Abstract excerpt

Prenatally acquired human cytomegalovirus (HCMV) infection is the most frequent viral infection of newborns in developed countries. Virostatic therapy is accompanied by side effects and stepwise emergence of resistant virus variants. Different genotypic approaches show limited sensitivity in detecting on-growing minor resistant virus populations. Here, we demonstrate the superiority of pyrosequencing for the...

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Identifiers

PMID: 21165648
DOI: 10.1007/s00430-010-0181-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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